Characterization of blaOxA-23 gene regions in isolates of Acinetobacter baumannii
نویسندگان
چکیده
منابع مشابه
Drug-resistant gene of blaOXA-23, blaOXA-24, blaOXA-51 and blaOXA-58 in Acinetobacter baumannii.
We distinguished the four alleles of OXA subgroups from 339 strains of Acinetobacter baumannii using Polymerase Chain Reaction, and investigated distributions of OXA subgroups in clinical isolated strains. A total of 196 Acinetobacter baumannii were isolated from the Central Hospital of Zhumadian between 2010 and 2014. Amplification of OXA genes, blaOXA-23, blaOXA-24, blaOXA-51 and blaOXA-58, w...
متن کاملCharacterization of bla(OxA-23) gene regions in isolates of Acinetobacter baumannii.
BACKGROUND/PURPOSE To investigate the characterization of bla(OxA-23) gene regions in isolates of Acinetobacter baumannii from Taizhou Municipal Hospital. METHODS Fifty-nine non-repetitive, multiresistant (including imipenem-resistant) isolates of A. baumannii were recovered from clinical infections in hospitalized patients from January 2010 to August 2011 in Taizhou Municipal Hospital (affil...
متن کاملGenetics and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-23 in Acinetobacter baumannii.
The genetic structures surrounding the plasmid-carried blaOXA-23 oxacillinase gene, encoding resistance to carbapenems, were studied in Acinetobacter baumannii. ISAba1 and the novel element ISAba4 were detected upstream of the blaOXA-23 gene, providing promoter sequences for its expression. These insertion elements were likely involved in transposition processes at the origin of acquisition of ...
متن کاملFirst isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
Acinetobacter baumannii is frequently associated with nosocomial infections, and its increasing resistance to carbapenems may significantly reduce the choice of effective antibiotics (2). Since the first description of a carbapenem-hydrolyzing class D -lactamase (CHDL), ARI-1 (renamed OXA-23), from a clinical isolate of A. baumannii in Scotland in 1995 (11), the corresponding blaOXA-23 gene has...
متن کاملAbaR4-type resistance island including the blaOXA-23 gene in Acinetobacter nosocomialis isolates.
This study reports for the first time the AbaR4-type resistance island with the bla(OXA-23) gene in two carbapenem-resistant A. nosocomialis isolates from South Korea and Thailand.
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ژورنال
عنوان ژورنال: Journal of Microbiology, Immunology and Infection
سال: 2015
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2014.01.007